Colgate<sup>®</sup> Enamel Health<sup>™</sup> Toothpaste

Colgate® Enamel Health Toothpaste

Replenishes natural calcium and phosphate back into weakened enamel, filling in rough spots

Ingredients

Active ingredients

Sodium Fluoride 0.24%, 0.15 % Fluoride w/v fluoride ion

Inactive ingredients

Water, sorbitol, hydrated silica, glycerin, PEG-12, tetrasodium pyrophosphate, sodium lauryl sulfate, flavor, microcrystalline cellulose, zinc phosphate, cellulose gum, cocamidopropyl betaine, benzyl alcohol, sodium saccharin, xanthan gum, mica, titanium dioxide, FD&C blue no. 1.

Mode of Action

Colgate® Enamel Health Toothpaste works to help transform enamel in 2 ways:

  • Formulated to help replenish natural calcium and other minerals back into weakened enamel, filling in rough spots and making it stronger.
  • Gently polishes the enamel surface with gentle micro-polishing action, so germs are less likely to stick

Proof of Efficacy

50% Stronger Protection Against Acid Attacks*

A pH-cycling model lab study was conducted to measure the enamel protection mode of action of Colgate® Enamel Health toothpaste versus ordinary fluoride toothpaste (non-antibacterial). An in vitro methodology was employed using a robotic instrument. Enamel substrates (N=6 per cell) were prepared by embedding bovine incisors in methacrylate-based resin and polishing for a fixed time period so that all samples were visually comparable and had similar levels of hardness at the beginning of the study. Prior to testing, all enamel substrates were pre-etched with 5% citric acid for 30 seconds. Half of the substrate was masked with acid resistant tape to protect the surface as a control surface.

The testing methodology alternated 1 minute toothpaste treatment periods with 2 minute acid exposure periods according to the daily sequence of T – C – C – C – C – T (T=toothpaste treatment, C=acid challenge). The acid challenge was performed with a 1% aqueous solution of citric acid (pH 3.8). Between every treatment and challenge cycle, all enamel substrates were kept in a sterile artificial saliva solution at 37 °C.

After this regimen was conducted for 5 days, the change in micro hardness was measured. The use of a programmed robot allowed for the highest accuracy in conducting the protocol over 5 days. All substrates were exposed to treatment and challenge cycle at the same temperature and time.

*Compared to ordinary fluoride toothpaste (non-antibacterial).